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Fifteen-minute consultation: a structured approach to the child with primary amenorrhea
  1. Rachel Varughese1,
  2. Fiona Ryan2,
  3. Tafadzwa Makaya2
  1. 1 Department of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
  2. 2 Paediatric Endocrinology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
  1. Correspondence to Dr Rachel Varughese, Oxford University Hospitals NHS Foundation Trust, Oxford OX33 1YG, UK; rachel.varughese{at}


Puberty is a life-changing time in the life of a young person, with physical, psychological and social considerations. Amenorrhea is derived from Latin: a—‘not’, men—‘month’ and rhein—‘flow’, meaning absence of monthly flow. In medical terms, it is a symptom describing absence of menstruation. It can be classified as either primary or secondary. This article will focus solely on primary amenorrhea. Primary amenorrhea can induce great anxiety in both the patient and the family and often presents to the general paediatrician. A thorough history and examination and judicious use of investigations is crucial to ensure timely diagnosis and management.

  • general paediatrics
  • endocrinology
  • adolescent health

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  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; externally peer reviewed.

  • Data availability statement There are no data in this work