Immunotherapy is a promising area of therapy in patients with neuro-oncological malignancies.
However, early-phase studies show unique challenges associated with the assessment …

Magnetic resonance imaging (MRI) evaluation of the developing brain has dramatically
increased over the last decade. Faster acquisitions and the development of advanced MRI …

Magnetic resonance spectroscopy (MRS) offers a unique, noninvasive approach to assess
pediatric neurological abnormalities at microscopic levels by quantifying cellular metabolites. …

It is important to devise new strategies to derive value from lignin, which is a potential waste
by-product from paper industries and present day biorefineries. In this research, we report, …

The sudden infant death syndrome (SIDS) is postulated to result from a failure of homeostatic
responses to life-threatening challenges (eg asphyxia, hypercapnia) during sleep. The …

Electrocardiogram (ECG) is widely used technique in study of heart beat irregularities such
as cardiac arrhythmias, sinus rhythms and heart failure. It is a significant and popular …

Background Karen Ann Quinlan had a cardiopulmonary arrest in 1975 and died 10 years
later, having never regained consciousness. Her story prompted a national debate about the …

PURPOSE: Our aims were to evaluate the metabolic profiles of pediatric brain tumors with
short echo time (TE) MR spectroscopy and absolute quantitation of metabolite concentrations (…

Purpose Diffuse brainstem gliomas (BSGs) and other high-grade gliomas (HGGs) of childhood
carry a dismal prognosis despite current treatments, and new therapies are needed. …

Background Paediatric low-grade glioma is the most common CNS tumour of childhood.
Although overall survival is good, disease often recurs. No single universally accepted …