The burden of pediatric asthma

W Lenney - Pediatric Pulmonology, 1997 - Wiley Online Library
Childhood asthma is common and its prevalence is increasing in most countries of the
world. Large‐scale studies indicate that approximately one‐third of children with asthma …

Hydrogen cyanide, a volatile biomarker of Pseudomonas aeruginosa infection

D Smith, P Španěl, FJ Gilchrist… - Journal of breath …, 2013 - iopscience.iop.org
Since we first recognized the regular presence of gaseous hydrogen cyanide, HCN, in the
headspace of plate cultures of the bacterium Pseudomonas aeruginosa, PA, derived from …

Detection of volatile compounds emitted by Pseudomonas aeruginosa using selected ion flow tube mass spectrometry

W Carroll, W Lenney, T Wang, P Španěl… - Pediatric …, 2005 - Wiley Online Library
Pseudomonas aeruginosa (PA) is associated with a distinctive smell produced by a
combination of volatile compounds (VCs). Selected ion flow tube mass spectrometry (SIFT …

Asthma severity and atopy: how clear is the relationship?

WD Carroll, W Lenney, F Child, RC Strange… - Archives of disease in …, 2006 - adc.bmj.com
Background: The relationship between asthma severity and atopy is complex. Many studies
have failed to show significant relationships between clinical severity or lung function and …

Isoprene levels in the exhaled breath of 200 healthy pupils within the age range 7–18 years studied using SIFT-MS

D Smith, P Španěl, B Enderby, W Lenney… - Journal of breath …, 2009 - iopscience.iop.org
The published results of breath isoprene studies, to date largely involving adults, are briefly
reviewed with special attention given to the work done on this topic during the last 10 years …

[HTML][HTML] How to match the optimal currently available inhaler device to an individual child with asthma or recurrent wheeze

WM Van Aalderen, L Garcia-Marcos, M Gappa… - NPJ primary care …, 2015 - nature.com
Inhaled medications are the cornerstone of treatment in early childhood wheezing and
paediatric asthma. A match between patient and device and a correct inhalation technique …

Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection

FJ Gilchrist, RJ Bright-Thomas, AM Jones… - Journal of breath …, 2013 - iopscience.iop.org
Elevated concentrations of hydrogen cyanide (HCN) have been detected in the headspace
of Pseudomonas aeruginosa (PA) cultures and in the breath of children with cystic fibrosis …

[HTML][HTML] Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects

W Lenney, F Edenborough, P Kho, JM Kovarik - Journal of Cystic Fibrosis, 2011 - Elsevier
BACKGROUND: Reducing nebulisation times for tobramycin solution for inhalation in cystic
fibrosis (CF) may improve compliance. METHODS: In this single-dose, open-label, two-way …

Improving the global diagnosis and management of asthma in children

W Lenney, A Bush, DA Fitzgerald, M Fletcher, A Ostrem… - Thorax, 2018 - thorax.bmj.com
Asthma is the most common chronic condition in children worldwide. It affects daytime
activities, sleep and school attendance and causes anxiety to parents, families and other …

Preschool healthcare utilisation related to home oxygen status

A Greenough, J Alexander, S Burgess… - Archives of Disease in …, 2006 - fn.bmj.com
Objective: To determine, in prematurely born children who had bronchopulmonary dysplasia
(BPD), if respiratory morbidity, healthcare utilisation, and cost of care during the preschool …