Biological nitrogen fixation is an important source of fixed nitrogen for the biosphere.
Microorganisms catalyse biological nitrogen fixation with the enzyme nitrogenase, which …

Because viruses of eukaryotic algae are incredibly diverse, sweeping generalizations about
their ecology are rare. These obligate parasites infect a range of algae and their diversity …

Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of
genetic variation. We present a microfluidics-based, linked-read sequencing technology that …

We have solved the structure of Escherichia coli cytidine deaminase (CDA) complexed to
the transition state analog, 5-fluoroprimidin-2-one riboside. The monomer of the α 2 CDA …

The scope for ecological studies of eukaryotic algal viruses has greatly improved with the
development of molecular and bioinformatic approaches that do not require algal cultures …

Background: Efavirenz is a second-generation non-nucleoside inhibitor of HIV-1 reverse
transcriptase (RT) that has recently been approved for use against HIV-1 infection …

Orotidine 5′-phosphate decarboxylase produces the largest rate enhancement that has
been reported for any enzyme. The crystal structure of the recombinant Saccharomyces …

Despite the progress of the past two decades, there is still considerable need for safe,
efficacious drugs that target human immunodeficiency virus (HIV). This is particularly true for …

To compare the difference in the degree of pain and functional disability of the shoulder in
patients who underwent neck dissection for the treatment of head and neck cancer, 23 …

Modification by covalent attachment of polyethylene glycol (PEG) can reduce the
immunogenicity and prolong the circulating life of proteins, but the utility of this approach for …