Previously published guidelines for the diagnosis and management of primary immune
thrombocytopenia (ITP) require updating largely due to the introduction of new classes of …

While most would agree that the mid-seventies were vintage years for endor phin research,
1982 is certain to be" a very good year." Less obvious to the public eye, it is nevertheless a …

The cloning of the opioid receptors has profoundly affected our understanding of opioid-
receptor expression, regulation and function. This review focuses on the impact that cloning …

Background Mortality statistics are fundamental to public health decision making. Mortality
varies by time and location, and its measurement is affected by well known biases that have …

Background Before 2020, mental disorders were leading causes of the global health-related
burden, with depressive and anxiety disorders being leading contributors to this burden. The …

Animal experiments remain essential to understand the fundamental mechanisms
underpinning malignancy and to discover improved methods to prevent, diagnose and treat …

Researchers commonly report that families of children with autism spectrum disorder (ASD)
experience more parenting stress than families of typically developing (TD) children or those …

Measurements of the thermal conductivity above 30 K of mixed crystals with controlled
disorder,(KBr) 1− x (KCN) x,(NaCl) 1− x,(NaCn) x Zr 1− x Y x O 2− x/2, and Ba 1− x La x F 2+ …

Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …

This article describes the development and preliminary validation of a brief questionnaire
that assesses exposure to a broad range of potentially traumatic events. Items were …