It is a common belief that we are more susceptible to infections when deprived of sleep.
Consistent with this, there is increasing evidence that sleep deprivation has detrimental …

Two developments are set to revolutionise research in and clinical management of
infectious diseases. First, the completion of the human genome project together with the …

Few studies are available to inform duration of intravenous antibiotics for children and when
it is safe and appropriate to switch to oral antibiotics. We have systematically reviewed …

Acute rheumatic fever is a major cause of heart disease in large parts of the world, but it
remains unknown why only a small fraction of those who are infected with rheumatogenic …

Background: There are no guidelines for the management of brain abscesses in children,
and there is a paucity of recent data describing clinical and microbiologic features. We …

Background: Infection with antibiotic-resistant (AR) Gram-negative (GN) bacteria is
associated with increased morbidity and mortality. The aim of this study was to determine …

Objective To determine if a simple stimulation method increases the rate of infant voiding for
clean catch urine within five minutes. Design Randomised controlled trial. Setting …

Due to the early administration of antibiotics, meningococcal disease is increasingly difficult
to diagnose by culturing. Laboratory studies have shown PCR to be sensitive and specific …

Pathogenic yeast forms are commonly associated with invasive fungal disease in the
immunocompromised host, including patients with haematological malignancies and …

Hagerstown, after broad-spectrum antibiotic therapy, thus suggesting a bacterial orchi-
epididymitis rather than due to SARS-CoV-2. On the other hand, if testis was a privileged …