[HTML][HTML] Management of acute respiratory diseases in the pediatric population: the role of oral corticosteroids
Respiratory diseases account for about 25% of all pediatric consultations, and 10% of these
are for asthma. The other main pediatric respiratory diseases, in terms of incidence, are …
are for asthma. The other main pediatric respiratory diseases, in terms of incidence, are …
[HTML][HTML] Asthma: differential diagnosis and comorbidities
N Ullmann, V Mirra, A Di Marco, M Pavone… - Frontiers in …, 2018 - frontiersin.org
Childhood asthma remains a multifactorial disease with heterogeneous clinical phenotype
and complex genetic inheritance. The primary aim of asthma management is to achieve …
and complex genetic inheritance. The primary aim of asthma management is to achieve …
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma
S Saglani, S Lui, N Ullmann, GA Campbell… - Journal of allergy and …, 2013 - Elsevier
Background TH 2 cytokines are not responsible for the ongoing symptoms and pathology in
children with severe therapy-resistant asthma (STRA). IL-33 induces airway …
children with severe therapy-resistant asthma (STRA). IL-33 induces airway …
[HTML][HTML] Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
S Castanhinha, R Sherburn, S Walker, A Gupta… - Journal of Allergy and …, 2015 - Elsevier
Background The mechanism underlying severe asthma with fungal sensitization (SAFS) is
unknown. IL-33 is important in fungus-induced asthma exacerbations, but its role in fungal …
unknown. IL-33 is important in fungus-induced asthma exacerbations, but its role in fungal …
Increased airway smooth muscle in preschool wheezers who have asthma at school age
R O'Reilly, N Ullmann, S Irving, CJ Bossley… - Journal of Allergy and …, 2013 - Elsevier
BACKGROUND: Increased airway smooth muscle (ASM) is a feature of established asthma
in schoolchildren, but nothing is known about ASM in preschool wheezers. OBJECTIVE: We …
in schoolchildren, but nothing is known about ASM in preschool wheezers. OBJECTIVE: We …
[HTML][HTML] Difficult and severe asthma in children
F Porcaro, N Ullmann, A Allegorico, A Di Marco… - Children, 2020 - mdpi.com
Asthma is the most frequent chronic inflammatory disease of the lower airways affecting
children, and it can still be considered a challenge for pediatricians. Although most …
children, and it can still be considered a challenge for pediatricians. Although most …
Phenotype characterisation of TBX4 mutation and deletion carriers with neonatal and paediatric pulmonary hypertension
C Galambos, MP Mullen, JT Shieh… - European …, 2019 - Eur Respiratory Soc
Rare variants in the T-box transcription factor 4 gene (TBX4) have recently been recognised
as an emerging cause of paediatric pulmonary hypertension (PH). Their pathophysiology …
as an emerging cause of paediatric pulmonary hypertension (PH). Their pathophysiology …
Assessment of corticosteroid response in pediatric patients with severe asthma by using a multidomain approach
CJ Bossley, L Fleming, N Ullmann, A Gupta… - Journal of Allergy and …, 2016 - Elsevier
Background There is no agreed upon definition of systemic corticosteroid response in
asthmatic children. Moreover, pediatric severe therapy-resistant asthma (STRA) is …
asthmatic children. Moreover, pediatric severe therapy-resistant asthma (STRA) is …
Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis
A Ravelli, M Ioseliani, X Norambuena… - … : Official Journal of …, 2007 - Wiley Online Library
Methods. The study group comprised 177 patients with polyarticular JIA. Radiographs of the
wrist/hand of each patient were obtained at baseline (first observation) and then at 1, 3, 5 …
wrist/hand of each patient were obtained at baseline (first observation) and then at 1, 3, 5 …
Modifiable risk factors associated with bronchiolitis
Background: We sought to clarify possibly modifiable risk factors related to pollution
responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational …
responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational …