What is CRISPR/Cas9?

M Redman, A King, C Watson, D King - Archives of Disease in …, 2016 - ep.bmj.com
Clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 is a gene-editing
technology causing a major upheaval in biomedical research. It makes it possible to correct …

[HTML][HTML] Cocaine: what is the crack? A brief history of the use of cocaine as an anesthetic

M Redman - Anesthesiology and pain medicine, 2011 - ncbi.nlm.nih.gov
Cocaine: What is the Crack? Redman M for anesthesia because the most important
developments in the anesthetic use of cocaine occurred in 1880s. Nowadays, such a delay …

Low-level laser therapy for oral mucositis in children with cancer

MG Redman, K Harris, BS Phillips - Archives of Disease in Childhood, 2022 - adc.bmj.com
Objective To assess the efficacy of oral low-level laser therapy (LLLT)–also known as
photobiomodulation–in the reduction of oral mucositis experienced by children and young …

[HTML][HTML] Biallelic PRMT7 pathogenic variants are associated with a recognizable syndromic neurodevelopmental disorder with short stature, obesity, and craniofacial …

E Cali, M Suri, M Scala, MP Ferla, S Alavi, EA Faqeih… - Genetics in …, 2023 - Elsevier
Purpose Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes
that catalyzes the methylation of arginine residues on several protein substrates. Biallelic …

Care of the dying: a qualitative exploration of foundation year doctors' experiences

M Redman, J Pearce, S Gajebasia… - Medical …, 2017 - Wiley Online Library
Context Foundation Year doctors (FY s), who are newly qualified, are expected to provide
care for dying patients. Experiences at this early mandatory stage of training may form the …

[HTML][HTML] Expanding SPTAN1 monoallelic variant associated disorders: From epileptic encephalopathy to pure spastic paraplegia and ataxia

H Morsy, M Benkirane, E Cali, C Rocca… - Genetics in …, 2023 - Elsevier
Purpose Nonerythrocytic αII-spectrin (SPTAN1) variants have been previously associated
with intellectual disability and epilepsy. We conducted this study to delineate the phenotypic …

Academic poster design at a national conference: a need for standardised guidance?

A Gopal, M Redman, D Cox, D Foreman… - The Clinical …, 2017 - Wiley Online Library
Background Academic posters are a common means of disseminating information at
conferences. Presentation at conferences is frequently given weight in postgraduate training …

Ancestry, race and ethnicity: the role and relevance of language in clinical genetics practice

MG Redman, RH Horton, H Carley… - Journal of Medical …, 2024 - jmg.bmj.com
Background The terms ancestry, race and ethnicity are used variably within the medical
literature and within society and clinical care. Biological lineage can provide an important …

[HTML][HTML] The role of virtual consultations in cancer genetics: challenges and opportunities introduced by the COVID-19 pandemic

MG Redman, V Aguda, R Dore, JO Lim, B Speight… - BJC Reports, 2023 - nature.com
The COVID-19 pandemic changed the delivery of healthcare within the United Kingdom. A
virtual model of care, utilising telephone and video consultations, was rapidly imposed upon …

Monoallelic loss-of-function BMP2 variants result in BMP2-related skeletal dysplasia spectrum

JRC Priestley, AR Deshwar, H Murthy… - Genetics in …, 2023 - Elsevier
Abstract Purpose Bone morphogenic proteins (BMPs) regulate gene expression that is
related to many critical developmental processes, including osteogenesis for which they are …