The overall survival of childhood rhabdomyosarcoma has improved dramatically over the
past 10 years. Early diagnosis and appropriate referral to a specialised centre leading to an …

Signaling by the transcription factor nuclear factor kappa B (NF-κB) involves its release from
inhibitor kappa B (IκB) in the cytosol, followed by translocation into the nucleus. NF-κB …

BACKGROUND: Sacrococcygeal teratoma (SCT) is uncommon (1: 35,000-1: 40,000
newborns). We report a 25-year single-center experience with a focus on late effects …

Neuroblastoma is the most frequently diagnosed extracranial solid tumour in childhood.
While a subset of tumours show spontaneous regression or complete remission following …

The role of histone deacetylase (HDAC) 4 and 6 in glioblastoma (GBM) radioresistance was
investigated. We found that tumor samples from 31 GBM patients, who underwent …

Rhabdomyosarcoma (RMS) is a common childhood solid tumor, resulting from
dysregulation of the skeletal myogenesis program. Two major histological subtypes occur in …

Background Rhabdomyosarcoma (RMS) is a highly malignant tumour accounting for nearly
half of soft tissue sarcomas in children. MicroRNAs (miRNAs) represent a class of short, non …

Coexpression for c‐Kit receptor and its ligand stem cell factor (SCF) has been described in
neuroblastoma (NB) cell lines and tumors, suggesting the existence of an autocrine loop …

Background Rhabdomyosarcoma (RMS) is the most commonly diagnosed malignant soft
tissue tumour in children and adolescents. Aberrant expression of Anaplastic Lymphoma …

This is the fourth official document of the SIOP Working Committee on psychosocial issues in
pediatric oncology constituted in 1991. This document develops another topic discussed …