User profiles for "author:Eslam Al-Abadi"

Eslam Al-Abadi

Consultant Paediatric Rheumatologist, Birmingham Women's and Children's Hospital
Verified email at nhs.net
Cited by 3844

[HTML][HTML] Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2021 - thelancet.com
Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients
admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. Methods …

[HTML][HTML] Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS): cardiac features, management and short-term outcomes …

T Ramcharan, O Nolan, CY Lai, N Prabhu… - Pediatric …, 2020 - Springer
Children were relatively spared during COVID-19 pandemic. However, the recently reported
hyperinflammatory syndrome with overlapping features of Kawasaki disease and toxic shock …

[HTML][HTML] Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2021 - thelancet.com
Background Many patients with COVID-19 have been treated with plasma containing anti-
SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent …

[HTML][HTML] Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Casirivimab and imdevimab are non-competing monoclonal antibodies that
bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike …

[HTML][HTML] Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-
thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients …

[PDF][PDF] Muscle biopsy findings in combination with myositis‐specific autoantibodies aid prediction of outcomes in juvenile dermatomyositis

CT Deakin, SA Yasin, S Simou, KA Arnold… - Arthritis & …, 2016 - Wiley Online Library
Objective Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition
characterized by rash and proximal muscle weakness. While some patients respond to …

[PDF][PDF] The immune landscape of SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Children (MIS-C) from acute disease to recovery

E Syrimi, E Fennell, A Richter, P Vrljicak, R Stark, S Ott… - Iscience, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening disease
occurring several weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Anti-tumour necrosis factor treatment for the prevention of ischaemic events in patients with deficiency of adenosine deaminase 2 (DADA2)

S Cooray, E Omyinmi, Y Hong, C Papadopoulou… - …, 2021 - academic.oup.com
Objective To evaluate the impact of anti-Tumour Necrosis Factor-α (anti-TNF) treatment on
the occurrence of vasculitic ischaemic events in patients with deficiency of adenosine …

[HTML][HTML] Serology confirms SARS-CoV-2 infection in PCR-negative children presenting with paediatric inflammatory multi-system syndrome

M Perez-Toledo, SE Faustini, SE Jossi, AM Shields… - MedRxiv, 2020 - ncbi.nlm.nih.gov
Background During the COVID-19 outbreak, reports have surfaced of children who present
with features of a multisystem inflammatory syndrome with overlapping features of Kawasaki …

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK

JS Massias, EMD Smith, E Al-Abadi, K Armon… - Lupus, 2021 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease.
Patients diagnosed with juvenile-onset SLE (jSLE), when compared to individuals with adult …