The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease

T Yang, EM Richards, CJ Pepine… - Nature Reviews …, 2018 - nature.com
Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …

Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review

ND Iadarola, MJ Niciu, EM Richards… - … advances in chronic …, 2015 - journals.sagepub.com
Current pharmacotherapies for major depressive disorder (MDD) and bipolar depression
(BDep) have a distinct lag of onset that can generate great distress and impairment in …

Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder

MJ Niciu, DF Ionescu, EM Richards… - Journal of neural …, 2014 - Springer
Monoaminergic neurotransmitter (serotonin, norepinephrine and dopamine) mechanisms of
disease dominated the research landscape in the pathophysiology and treatment of major …

Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure

S Kim, R Goel, A Kumar, Y Qi, G Lobaton… - Clinical …, 2018 - portlandpress.com
Recent evidence indicates a link between gut pathology and microbiome with hypertension
(HTN) in animal models. However, whether this association exists in humans is unknown …

Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or …

BR Stevens, R Goel, K Seungbum, EM Richards… - Gut, 2018 - gut.bmj.com
We read with interest the recent work by Uhde et al, 1 which demonstrated that physically
asymptomatic non-coeliac gluten/wheat sensitivity involves compromised intestinal …

Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety

ED Ballard, DF Ionescu, JLV Voort, MJ Niciu… - Journal of psychiatric …, 2014 - Elsevier
Objective Suicide is a psychiatric emergency. Currently, there are no approved
pharmacologic treatments for suicidal ideation. Ketamine is an N-methyl-D-aspartate …

Do the dissociative side effects of ketamine mediate its antidepressant effects?

DA Luckenbaugh, MJ Niciu, DF Ionescu… - Journal of affective …, 2014 - Elsevier
Background The N-methyl-d-aspartate receptor antagonist ketamine has rapid
antidepressant effects in major depression. Psychotomimetic symptoms, dissociation and …

Hyperoxic reperfusion after global ischemia decreases hippocampal energy metabolism

EM Richards, G Fiskum, RE Rosenthal, I Hopkins… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Previous reports indicate that compared with normoxia, 100%
ventilatory O2 during early reperfusion after global cerebral ischemia decreases …

Altered gut microbiome profile in patients with pulmonary arterial hypertension

S Kim, K Rigatto, MB Gazzana, MM Knorst… - …, 2020 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is considered a disease of the pulmonary
vasculature. Limited progress has been made in preventing or arresting progression of PAH …

Clinical predictors of ketamine response in treatment-resistant major depression

MJ Niciu, DALDF Ionescu, S Guevara… - The Journal of clinical …, 2014 - psychiatrist.com
Objective: The N-methyl-d-aspartate receptor antagonist ketamine has rapid antidepressant
effects in treatment-resistant major depressive disorder (MDD) and bipolar depression …