Puberty is a defining phase of human development where growth ends and the ability to
reproduce begins. An understanding of the events leading up to puberty highlights the fact …

Children with Duchenne muscular dystrophy (DMD) are shorter than their healthy peers. The
introduction of corticosteroid (CS) has beneficial effects on muscle function but slows growth …

Glucocorticoids (GCs) are effective for the treatment of many chronic conditions, but their use
is associated with frequent and wide-ranging adverse effects including osteoporosis and …

Background Accelerated infant weight gain in individuals born full term is linked to
cardiovascular risk in adulthood, but data in those born preterm are inconsistent. Objective …

The effects of preterm birth and perinatal events on bone health in later life remain largely
unknown. Bone mineral density (BMD) and osteoporosis risk may be programmed by early …

Objective: Distal myopathies are a diagnostically challenging group of diseases. We wanted
to understand the value of MRI in the current clinical setting and explore the potential for …

Following a diagnosis of a developmental disorder such as autism spectrum disorder (ASD)
in early childhood, parents may decide to have fewer children than previously planned. The …

Background An estimated 11% of births occur preterm, and survival is improving. Early
studies suggested an association between preterm birth and earlier puberty. Given the …

Objective First-line treatment of thyrotoxicosis in young people is thionamide anti-thyroid
drug (ATD) in a blocking dose with levothyroxine replacement (block and replace, BR) or in …

Background Achieving adequate nutrition in preterm infants is challenging. The post-
discharge period may be critical for influencing growth and cognitive outcomes. We studied …