A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO

Br J Haematol. 2006 Dec;135(5):603-33. doi: 10.1111/j.1365-2141.2006.06343.x.

Abstract

The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Blood Coagulation Disorders, Inherited / diagnosis
  • Blood Coagulation Disorders, Inherited / therapy
  • Blood Platelet Disorders / diagnosis
  • Blood Platelet Disorders / therapy
  • Blood Platelets / physiology
  • Female
  • Hematologic Diseases / diagnosis*
  • Hematologic Diseases / therapy
  • Hemorrhagic Disorders / diagnosis
  • Hemorrhagic Disorders / therapy
  • Humans
  • Infant, Newborn
  • Pregnancy