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A fatal case of cerebral oedema with hyponatraemia and massive polyuria after renal transplantation

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Abstract

We report the case of a child who died from severe cerebral oedema in the context of hyponatraemia and extreme polyuria immediately after renal transplantation. The patient was treated according to a standard post-transplantation protocol, receiving 0.45% saline solution for urine output replacement. The case highlights the dangers of massive fluid therapy in the context of polyuria and, therefore, the need for intensive monitoring.

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Authors and Affiliations

  1. Department of Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK

    Janette Cansick, Lesley Rees, William Van’t Hoff & Detlef Bockenhauer

  2. Pediatrics, Royal Free Hospital, Hampstead, London, UK

    Janette Cansick

  3. Transplant Surgery, Guy’s and St. Thomas’ Hospital, London, UK

    Geoff Koffman

Authors
  1. Janette Cansick
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  2. Lesley Rees
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  3. Geoff Koffman
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  4. William Van’t Hoff
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  5. Detlef Bockenhauer
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Correspondence to Detlef Bockenhauer.

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Cansick, J., Rees, L., Koffman, G. et al. A fatal case of cerebral oedema with hyponatraemia and massive polyuria after renal transplantation. Pediatr Nephrol 24, 1231–1234 (2009). https://doi.org/10.1007/s00467-008-1100-y

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  • DOI: https://doi.org/10.1007/s00467-008-1100-y

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