Antibiotic choice (3-day course for prophylaxis, 5-day course for treatment)
| Children <1 month of age | Seek specialist advice |
| First choice oral antibiotic (Child aged >1 month and <18 years) | Co-amoxiclav |
| Alternative choice oral antibiotic Child <12 years (if penicillin allergy or co-amoxiclav unsuitable) | Co-trimoxazole (off-label use) See British National Formulary (BNF) for Children for monitoring requirements |
| Alternative choice oral antibiotic Child 12–17 years (if penicillin allergy or co-amoxiclav unsuitable) | Doxycycline with metronidazole |
| First choice intravenous antibiotic (unable to take oral or severely ill) (child aged >1 month and <18 years) | Co-amoxiclav |
| Alternative choice of intravenous antibiotic (penicillin allergy or co-amoxiclav unsuitable) (child aged >1 month and <18 years) | Cefuroxime or cefotaxime with
metronidazole |
| If cephalosporin not appropriate, seek microbiology advice | |