Prolonged capillary refill time | CRP >300 mg/L | Abnormal ECG (arrythmias and heart block) |
Hypotension/shock and/or tachycardia | Increasing troponin and NT-proBNP | Coronary artery aneurysms, myocardial dysfunction |
Fluid resuscitation with 20 mL/kg fluid boluses or absent/ paradoxical response | Increasing lactate, LDH, ferritin, D-dimer | Cardiomegaly |
Respiratory failure | Increasing creatinine | Neurological compromise |
No response to IVIG/steroids | Young children (<1 year old) |
CRP, C reactive protein; IVIG, intravenous immunoglobulin; LDH, lactic acid dehydrogenase; NT-proBNP, N-terminal pro-B type natriuretic peptide.