Table 1

Manufacturer reported LoD for the Food and Drug Administration-approved nucleic acid amplification tests

TestCompanyLoD (viral copies/mL)
Alinity mSARS-CoV-2 assayAbbott100
BioFire COVID-19 TestBioMérieux380
BioFire Respiratory Panel 2.1BioFire Diagnostics300
BioFire COVID-19 TestBioFire Defence, LLC330
Xpert Xpress SARS-CoV-2Cepheid250
Xpert Omni SARS-CoV-2Cepheid400
Panther Fusion SARS-CoV-2Hologic0.01*
Aptima SARS-CoV-2 assayHologic0.01*
Qiastat-Dx RespiratoryQiagen500
Aries SARS-CoV-2 assayLuminex1000
NxTAG CoV Extended Panel AssayLuminex5000
Simplexa COVID-19 direct assayDiaSorin Molecular242
2019-nCoV Real-Time RT-PCR Dx PanelCDC assay1000
ePlex Respiratory Pathogen Panel 2GenMark Diagnostics250
e-Plex SARS-CoV-2 testGenMark Diagnostics10
COVID-19 RT-PCRLabCorp COVID-196250
  • Adapted from COVID-19 infographic

  • *Denotes LoDs reported as median tissue culture infectious dose.

  • LoD, limit of detection; RT-PCR, reverse transcription PCR; TCID50, tissue culture infectious dose of virus that will produce infection in 50% of cell cultures inoculated in vitro.