Table 1

Manufacturer reported LoD for the Food and Drug Administration-approved nucleic acid amplification tests

Test	Company	LoD (viral copies/mL)
Alinity mSARS-CoV-2 assay	Abbott	100
BioFire COVID-19 Test	BioMérieux	380
BioFire Respiratory Panel 2.1	BioFire Diagnostics	300
BioFire COVID-19 Test	BioFire Defence, LLC	330
Xpert Xpress SARS-CoV-2	Cepheid	250
Xpert Omni SARS-CoV-2	Cepheid	400
Panther Fusion SARS-CoV-2	Hologic	0.01*
Aptima SARS-CoV-2 assay	Hologic	0.01*
Qiastat-Dx Respiratory	Qiagen	500
Aries SARS-CoV-2 assay	Luminex	1000
NxTAG CoV Extended Panel Assay	Luminex	5000
Simplexa COVID-19 direct assay	DiaSorin Molecular	242
2019-nCoV Real-Time RT-PCR Dx Panel	CDC assay	1000
ePlex Respiratory Pathogen Panel 2	GenMark Diagnostics	250
e-Plex SARS-CoV-2 test	GenMark Diagnostics	10
COVID-19 RT-PCR	LabCorp COVID-19	6250

Adapted from COVID-19 infographic https://csb.mgh.harvard.edu/covid.
*Denotes LoDs reported as median tissue culture infectious dose.
LoD, limit of detection; RT-PCR, reverse transcription PCR; TCID₅₀, tissue culture infectious dose of virus that will produce infection in 50% of cell cultures inoculated in vitro.