A recommendation for tumour surveillance in patients with hemihypertrophy:
Investigation | Frequency |
Genetics opinion: refer all patients | Once following initial paediatric consult |
Abdominal ultrasound scan: initially for all patients and post-genetic testing for those at >5% risk of tumours | 3 monthly, no less frequently than three times a year, until age 5–7 years |
Serum alpha fetoprotein: consider for those with methylation of IC2 defects or paternal uniparental disomy | 3 monthly until age 4 years If serum alpha fetoprotein rises: Repeat in 1 month and discuss with paediatric oncologist |
Clinician examination of the abdomen for masses | At clinic review, at least yearly, until discharge |