Table 1

The 10 warning signs for paediatric primary immune deficiency15

≥4 new ear infections within 1 yearRecurrent deep skin or organ abscesses
≥2 serious sinus infections within 1 yearPersistent thrush in mouth or fungal infection of skin
≥2 months of oral antibiotic treatment with little effect (possibly)Need for IV antibiotics to clear infections (possibly)
≥2 episodes of pneumonia within 1 year (depending on organism)≥2 deep-seated infections, including septicaemia
Failure of an infant to gain weight or grow normallyA family history of PID
  • PIDs, primary immune deficiencies.