Population | Pretest (background) probability of neuroblastoma | Test result | Post-test probability of neuroblastoma |
---|---|---|---|

Vague suspicion of neuroblastoma, non-specifically unwell child | 2% | Positive | 63% |

Negative | 0% | ||

Secondary care, distinct suspicion of neuroblastoma32 | 10% | Positive | 99% |

Negative | 1% | ||

Paraspinal or renal mass, strongly suspected neuroblastoma | 60% | Positive | 99.9% |

Negative | 18% | ||

Unilateral Horner's syndrome14 | 8% | Positive | 99% |

Negative | 1% | ||

Well infants ∼6 months old, screening investigation7 | 0.05% | Positive | 20% |

Negative | 0.01% | ||

Opsoclonus-myoclonus syndrome33 34 | 55% | Positive | 99.9% |

Negative | 15% |

Assumes average likelihood ratios (LR) for abnormal urine catecholamines of LR+ 85, LR− 0.15 (sensitivity ∼85% and specificity ∼99%).