Table 2

The effect of Tourette syndrome on the young person and their family QoL and CGB – modified and updated from Robertson (2011)

QoL
Group/authorsDate of studyCountryNumber and type subjectsSchedule/questionnaireResultsDomains affected
Storch et al432007USAYoungstersSelf-rep; Parents repTS=reduced c/f healthy controls; TS=higher c/f psych controlsTic severity
Bernard et al26 19212009USA58 youngstersTACQOLADHD (inattention); not tics
Cutler et al452009UK57 youngstersSelf-reportTic severity; ADHD; OCB
Hao et al462010China1335 (GTS and migraine)Paediatric QoL inventory (Peds QL 4.0)Patients scored lower than controls on allNot stated
Conelea et al472011USA232Internet-based survey with HRQoLTS have functional impairmentTic severity; comorbidity
Eddy et al482011aUK and Italy50 youngstersYQOL-RTS reduced QoLDepression; OCD. ADHD
Eddy et al492011bUK and Italy50 youngstersYQOL-RTS reduced QoLEven TS-only=reduced QoL; Tic severity; OCD; ADHD
Caregiver burden/parental stress
Cooper et al542003UK26 TS youngsters compared with 26 asthma youngstersGHQ; CGBParents of youngsters with TS;=more CGB; =increased psychopathologyOnly controlled study
Lee et al552007Taiwan150 parentsPSI; SSIFParents of GTS children have considerable stressGTS severity and family income affects parental stress most
  • ADHD, attention deficit hyperactivity disorder; CGB, caregiver burden; GHQ, General Health Questionnaire; GTS, Gilles de laTourette syndrome; HROL-R, health related quality of life; OCB, obsessive-compulsive behaviour; OCD, obsessive-compulsive disorder; QoL, quality of life; PSI, Parent Stress Index Form; Rep, report; SSIF, Social Support Index Form; YQOL, The Youth Quality of Life Instrument-Research Version.