Table 2

Rome III criteria for functional abdominal pain5

DiagnosisRome III criteria*
Functional abdominal pain▪ Episodic or continuous abdominal pain
▪ Insufficient criteria for other functional gastrointestinal disorders
Functional abdominal pain syndrome▪ Functional abdominal pain for at least 25% of the time and one or more of the following:
 1. Some loss of daily functioning
 2. Additional somatic symptoms such as headache, limb pain, or difficulty sleeping
Functional dyspepsia▪ Persistent or recurrent pain or discomfort centred in the upper abdomen
▪ Not relieved by defecation or associated with a change in stool frequency or form
Irritable bowel syndrome▪ Abdominal discomfort or pain associated with two or more of the following at least 25% of the time:
 1. Improved with defecation
 2. Onset associated with a change in frequency of stool
 3. Onset associated with a change in form of stool
Abdominal migraine▪ Paroxysmal episodes of intense, acute peri-umbilical pain that last for one or more hours.
▪ Intervening periods of usual health lasting weeks to months
▪ The pain interferes with normal activities
▪ The pain is associated with two or more of the following: anorexia, nausea, vomiting, headache, photophobia, pallor
  • *There must be no evidence of an inflammatory, anatomical, metabolic or neoplastic process to explain symptoms. Criteria must be fulfilled at least once a week for at least 2 months before diagnosis, except abdominal migraine where criteria must be fulfilled two or more times in the preceding 12 months.