System | Test/investigation | Yellow alert | Red alert |
---|---|---|---|
Nutrition | Body mass index | <2nd centile | |
Weight loss/week | >0.5 kg | >1.0 kg | |
Skin breakdown | <0.1 cm | 0.2 cm | |
Purpuric rash | Present | ||
Circulation | Systolic BP | <90 mmHg | <80 mmHg |
Diastolic BP | <70 mmHg | <60 mmHg | |
Postural drop | >10 mmHg | >20 mmHg | |
Pulse rate | <50/min | <40/min | |
Musculoskeletal | Unable to get up without using arms as balance | Yes | |
Unable to get up without using arms as leverage | Yes | ||
Unable to sit up without using arms as leverage | Yes | ||
Unable to sit up at all | Yes | ||
Temperature | <35°C (98.0°F) | <34.5°C (97.0°F) | |
FBC (looking for bone marrow depression) | WCC | <4.0 x 109/l | <2.0 x 109/l |
Neutrophils | <1.5 x 109/l | <1.0 x 109/l | |
Hb | <11.0 g/dl | <9.0 g/dl | |
Acute Hb drop | Yes | ||
Platelets | <130 x 109/l | <110 x 109/l | |
Electrolytes | Potassium | <3.5 mmol/l | <3.0 mmol/l |
Sodium | <135 mmol/l | <130 mmol/l | |
Magnesium | 0.5–0.7 mmol/l | <0.5 mmol/l | |
Phosphate | 0.5–0.8 mmol/l | <0.5 mmol/l | |
Urea | >7 mmol/l | >10 mmol/l | |
Liver function | Bilirubin | 20–40 μmol/l | >40 μmol/l |
Alk Phos * | 110–200 U/l | >200 U/l | |
AST | 40–80 IU/l | >80 IU/l | |
ALT | 45–90 U/l | >90 U/l | |
GGT | 45–90 U/l | >90 U/l | |
Albumin | <35 g/l | <32 g/l | |
CK | >170 ng/ml | >250 ng/ml | |
Glucose | <3.5 mmol/l | <2.5 mmol/l | |
ECG | Pulse rate | <50 | <40 |
QTc | >450 ms | ||
Arrhythmia | Present |
↵* Range for infant to 16 years old, 60–425 U/l.5
ALT, alanine aminotransferase; AST, aspartate transaminase; BP, blood pressure; CK, creatine kinase; ECG, electrocardiogram; FBC, full blood count; GGT, gamma-glutaryl transferase; Hb, haemoglobin; QTc, corrected QT interval on ECG; WCC, white cell count.