Physical examination findings that could point to primary immune deficiencies (PIDs)17
| General appearance | Poor weight gain Short stature Dysmorphism (eg, DiGeorge facies) |
| Ear, nose and throat | Chronically discharging ears Perforated tympanic membranes |
| Mouth | Severe gingivostomatitis Ulcers Recurrent or severe candidiasis Poor dentition |
| Lymphoid tissue | Excessive lymphadenopathy Absence of lymph nodes or tonsils Organomegaly |
| Skin | Severe eczema Neonatal erythroderma Severe BCG reaction Extensive warts or molluscum Albinism Telangiectasia Incontinentia pigmenti |
| Eyes | Retinal lesions Telangiectasia |
| Respiratory | Clubbing Signs respiratory infection |
BCG, Bacillus Calmette-Guerin.