Table 1

 The use of growth hormone (GH) therapy in short stature

NICE, National Institute for Clinical Excellence.
• Treatment recommended by NICE guidelines 2002 in the UK1
‐ GH deficiency, isolated or as part of multiple pituitary hormone deficiency
‐ Turner syndrome
‐ Prader Willi syndrome
‐ Short stature associated with chronic renal failure
• Licensed indications in Europe
‐ GH deficiency, isolated or as part of multiple pituitary hormone deficiency
‐ Turner syndrome
‐ Prader Willi syndrome
‐ Short stature associated with chronic renal failure
‐ Short stature associated with low birth weight
• Licensed in the USA, but not in Europe
‐ Idiopathic short stature
• Short stature conditions where there have been trials of treatment with GH but outcome is not clear (not licensed indications)
‐ Noonan syndrome
‐ Skeletal dysplasia
‐ Rheumatoid arthritis
‐ Down syndrome
‐ Short stature associated with prolonged steroid use
‐ Aarskog’s syndrome