Table 5

 Suggested “standard investigations” to be performed before the situation is regarded as a PUO

CRP, C reactive protein; ESR, erythrocyte sedimentation rate.
• Full blood count
• Urea and electrolytes
• Liver function tests
• Inflammatory markers: CRP, ESR
• Blood cultures when pyrexial
• Anti-streptolysin titre
• Viral serology including Epstein-Barr virus
• Throat swab: culture for viruses and bacteria
• Chest x ray
• Urinalysis and urine microscopy and culture
• Stool for microscopy and culture for bacteria and viruses
• Three thick blood films if malaria is a possibility