Table 3

 Side effects of isotretinoin

Dose related and predictable
Dryness of skin and mucous membranes including nose, eyes, and lips
Of particular concern
Teratogenicity, during treatment and for 6 weeks after stopping
Mood change—highly publicised, unproven, but cause for concern
Facial erythema, eczema, hair loss, and photosensitivity
Myalgia and arthralgia
Abnormalities of liver function
Elevation of triglycerides and cholesterol values
Bacterial overgrowth, particularly Staphylococcus aureus
Benign intracranial hypertension