Table 2

 The evidence behind the treatments for acute bronchiolitis

OxygenObservational studiesGive if oxygen saturation < 92%
AntibioticsControlled trial/observational studiesNot indicated routinely
BronchodilatorsSystematic reviewsOnly modest improvement in clinical score. Trial may be indicated
AdrenalineSystematic reviewSome benefit in outpatient setting. Trial may be indicated. Further research needed
SteroidsSystematic reviewNo evidence of benefit
Chest physiotherapySystematic review awaitedNo evidence of benefit currently
RibavirinSystematic reviewNo evidence although a suggestion of benefit in high risk infants. Consider if very ill infant with risk factors
RSV IgSystematic review awaitedNo evidence of benefit currently
PalivizumabRandomised controlled trialNo evidence of benefit currently