PT - JOURNAL ARTICLE AU - Abhishek Oswal AU - Jennifer Holman TI - Fifteen-minute consultation: Cardiac murmurs in the Newborn Infant Physical Examination (NIPE) AID - 10.1136/archdischild-2020-321206 DP - 2022 Oct 01 TA - Archives of disease in childhood - Education & practice edition PG - 326--329 VI - 107 IP - 5 4099 - http://ep.bmj.com/content/107/5/326.short 4100 - http://ep.bmj.com/content/107/5/326.full SO - Arch Dis Child Educ Pract Ed2022 Oct 01; 107 AB - The finding of a cardiac murmur on the initial newborn examination is common but may be a source of anxiety for practitioners due to worries about missing critical congenital heart defects (CHDs). This article aims to provide an approach to this common finding, in particular, reviewing the evidence base behind features of the history, examination and subsequent non-specialist investigations which may increase the likelihood of CHDs. The aim of this structured approach is to give clinicians confidence in dealing with this common clinical finding, to be able to pick out those infants most at risk of having critical CHDs.