PT - JOURNAL ARTICLE AU - Keightley, Jaclyn AU - Walsh, Jo AU - Bland, Ruth M TI - How to use autoantibodies in suspected paediatric rheumatic disease AID - 10.1136/archdischild-2021-323212 DP - 2022 Aug 01 TA - Archives of disease in childhood - Education & practice edition PG - 236--241 VI - 107 IP - 4 4099 - http://ep.bmj.com/content/107/4/236.short 4100 - http://ep.bmj.com/content/107/4/236.full SO - Arch Dis Child Educ Pract Ed2022 Aug 01; 107 AB - Autoantibodies can be an important indicator of paediatric rheumatic disease and useful in establishing a diagnosis. However, autoantibodies may be requested in cases where the patient does not have clinical features strongly suggestive of a rheumatic disease. This can lead to further unnecessary investigations, specialist referral and undue anxiety for the family. The aim of this article is to provide guidance for when it is appropriate to request autoantibodies, which ones to perform and how to interpret the results.