RT Journal Article SR Electronic T1 Adaptive trial designs: what is the continual reassessment method? JF Archives of disease in childhood - Education & practice edition JO Arch Dis Child Educ Pract Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 175 OP 177 DO 10.1136/archdischild-2019-316931 VO 106 IS 3 A1 Gerard Cathal Millen A1 Christina Yap YR 2021 UL http://ep.bmj.com/content/106/3/175.abstract AB