TY - JOUR T1 - Problem solving in clinical practice: the sick infant with low sodium and high potassium JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed SP - 23 LP - 27 DO - 10.1136/archdischild-2019-317756 VL - 106 IS - 1 AU - Yincent Tse AU - Nidhi Singhal AU - Leigh McDonald AU - Milan Gopal AU - Anupam Lall AU - Helen Johnstone AU - Timothy Cheetham Y1 - 2021/02/01 UR - http://ep.bmj.com/content/106/1/23.abstract N2 - Many paediatricians will be faced with a sick infant who on investigation is found to have hyponatraemia and hyperkalaemia at some time in their career. The focus of initial management includes the treatment of potentially life-threatening hyperkalaemia with concurrent investigation aiming to elucidate whether the underlying cause reflects a primarily renal or endocrine pathology. We describe the presentation of two infants who each presented with one of the more common underlying diagnoses that led to this biochemical disturbance and discuss the approach to immediate treatment, diagnostic work-up and longer term management. ER -