RT Journal Article
SR Electronic
T1 How to interpret a single cortisol measurement
JF Archives of disease in childhood - Education & practice edition
JO Arch Dis Child Educ Pract Ed
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 347
OP 351
DO 10.1136/archdischild-2019-318431
VO 105
IS 6
A1 Meera Shaunak
A1 Joanne C Blair
A1 Justin Huw Davies
YR 2020
UL http://ep.bmj.com/content/105/6/347.abstract
AB Adrenal insufficiency can present with non-specific clinical features. Therefore, a single cortisol measurement is often included in the biochemical work-up of an unwell child. This article aims to review the diagnostic utility of a single cortisol measurement by outlining the physiological, clinical and technical factors affecting result interpretation. Clinical scenarios are used to illustrate how this test may be used in different commonly encountered situations in general paediatrics, with the aim of minimising the frequency of inconclusive results.