PT - JOURNAL ARTICLE AU - Bashaer Albulushi AU - Farah Thabet AU - Saad Alshahwan AU - Yasser Elborai AU - Nawaf Alkhayat AU - Mohamed Alshahrani AU - Brahim Tabarki TI - Problem-solving in clinical practice: breathing difficulty and muscle weakness following allogeneic haematopoietic stem cell transplantation AID - 10.1136/archdischild-2019-317281 DP - 2020 Sep 08 TA - Archives of disease in childhood - Education & practice edition PG - edpract-2019-317281 4099 - http://ep.bmj.com/content/early/2020/09/07/archdischild-2019-317281.short 4100 - http://ep.bmj.com/content/early/2020/09/07/archdischild-2019-317281.full AB - Acute weakness and dyspnoea are unusual presentation after allogeneic haematopoietic stem cell transplantation (HSCT) complicated by chronic graft-versus-host disease (GVHD). The differential diagnosis and management are challenging for the paediatrician. This case chronicles the diagnostic journey of a child who presented with weakness, dyspnoea and difficulty in speech, 2 years after allogeneic HSCT and GVHD and explores the approach to neurological manifestations in this context.