TY - JOUR T1 - An abnormal finding in the third trimester JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed DO - 10.1136/archdischild-2019-317455 SP - edpract-2019-317455 AU - Hannah Marshall AU - Kyle Petrie Y1 - 2019/12/10 UR - http://ep.bmj.com/content/early/2019/12/12/archdischild-2019-317455.abstract N2 - A healthy woman presented with an antepartum haemorrhage at 35/40 during a low-risk pregnancy with normal antenatal bloods and anomaly scan at 20/40 gestation. Following an abnormal ultrasound (USS), the baby was delivered by emergency C-section.A male infant was born in good condition but admitted to the neonatal unit for monitoring. Examination revealed global hypotonia, a weak uncoordinated suck and absent Moro reflex. He had widened sagittal sutures and a large posterior fontanelle. The remainder of the examination was unremarkable. Abnormal bloods are shown in table 1.View this table:In this windowIn a new windowTable 1 Initial newborn blood resultsHe was treated for suspected sepsis due to jaundice and temperature instability.Cranial USS was performed immediately (figure 1). Urgent MRI of the brain further characterised these abnormalities (figures 2–3).Figure 1 Coronal section of cranial ultrasound obtained on day 1 of life.Figure 2 Coronal section from MRI … ER -