PT  - JOURNAL ARTICLE
AU  - Tanmoy Chakrabarty
AU  - Sandya Tirupathi
AU  - Andrew Thompson
TI  - How to use: creatine kinase
AID  - 10.1136/archdischild-2019-317184
DP  - 2019 Jul 11
TA  - Archives of disease in childhood - Education & practice edition
PG  - edpract-2019-317184
4099  - http://ep.bmj.com/content/early/2019/07/11/archdischild-2019-317184.short
4100  - http://ep.bmj.com/content/early/2019/07/11/archdischild-2019-317184.full
AB  - Creatine kinase (CK) remains an essential tool for assessment of muscular weakness and pain in children despite the advent of advanced diagnostic tests in this field. It is also useful in diagnosing and monitoring various other conditions. This article will explore the physiology of CK and clinical situations where the estimation of CK can help the clinicians’ decision-making process with the diagnosis and management of these conditions. Some clinical scenarios are used to highlight how the tests can be used in different clinical situations. The role of CK as a biomarker of myocardial injury has been purposefully omitted in this article.