RT Journal Article SR Electronic T1 Fifteen-minute consultation: When medicines don’t work—the child with poorly controlled seizures JF Archives of disease in childhood - Education & practice edition JO Arch Dis Child Educ Pract Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 135 OP 140 DO 10.1136/archdischild-2018-316035 VO 104 IS 3 A1 Pooja Harijan A1 Arnab Kumar Seal A1 Manish Prasad A1 William P Whitehouse YR 2019 UL http://ep.bmj.com/content/104/3/135.abstract AB Drug-resistant epilepsy (DRE) occurs in 20%–30% of children with epilepsy with significant impact on their quality of life. Management of this group of children has greatly improved in the recent years with streamlining of epilepsy surgery services and associated quaternary multimodal evaluation. This article provides a review of DRE in children and management based on recent evidence and published opinion. We have also presented an algorithmic approach to the child with possible DRE.