PT - JOURNAL ARTICLE AU - Pooja Harijan AU - Arnab Kumar Seal AU - Manish Prasad AU - William P Whitehouse TI - Fifteen-minute consultation: When medicines don’t work—the child with poorly controlled seizures AID - 10.1136/archdischild-2018-316035 DP - 2019 Jun 01 TA - Archives of disease in childhood - Education & practice edition PG - 135--140 VI - 104 IP - 3 4099 - http://ep.bmj.com/content/104/3/135.short 4100 - http://ep.bmj.com/content/104/3/135.full SO - Arch Dis Child Educ Pract Ed2019 Jun 01; 104 AB - Drug-resistant epilepsy (DRE) occurs in 20%–30% of children with epilepsy with significant impact on their quality of life. Management of this group of children has greatly improved in the recent years with streamlining of epilepsy surgery services and associated quaternary multimodal evaluation. This article provides a review of DRE in children and management based on recent evidence and published opinion. We have also presented an algorithmic approach to the child with possible DRE.