RT Journal Article
SR Electronic
T1 Fifteen-minute consultation: Pharmacogenomics: a guide for busy clinicians
JF Archives of disease in childhood - Education & practice edition
JO Arch Dis Child Educ Pract Ed
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP edpract-2019-316971
DO 10.1136/archdischild-2019-316971
A1 Christopher Mark Parry
A1 Daniel Hawcutt
YR 2019
UL http://ep.bmj.com/content/early/2019/05/15/archdischild-2019-316971.abstract
AB The ultimate goal of pharmacogenomics is to understand how the effects of interindividual genetic variation impact on the response of patients to treatments and in turn optimise those treatments while minimising potential side effects. This review article provides a brief overview of pharmacogenomics, focusing on the methods used to understand how genes of interest are identified, how pharmacogenomics is currently used within paediatric clinical practice within the UK, potential areas for future use and some of the caveats specific to paediatric medicine.