TY - JOUR T1 - Fifteen-minute consultation: liver disease in children JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed SP - 170 LP - 176 DO - 10.1136/archdischild-2017-313036 VL - 103 IS - 4 AU - Jake P Mann AU - Kathy Gallagher AU - Emer Fitzpatrick AU - Anil Dhawan Y1 - 2018/08/01 UR - http://ep.bmj.com/content/103/4/170.abstract N2 - Liver disease in children can present in many ways from the frequently encountered prolonged neonatal jaundice to the comparatively rare acute liver failure. In this article, we will discuss ‘red flags’ of liver disease, the initial investigations required and when to refer to a specialist liver centre. Across all presentations, the degree of elevation of alanine aminotransferase or aspartate aminotransferase provides only little diagnostic information. Measurement of clotting is vital, and coagulopathy should be followed by a trial of intravenous vitamin K before being repeated. ER -