TY - JOUR T1 - Concomitant administration of methotrexate does not improve efficacy of intra-articular joint injections in patients with oligoarticular juvenile idiopathic arthritis JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed DO - 10.1136/archdischild-2017-313926 SP - edpract-2017-313926 AU - William J Coles AU - Eslam Al-Abadi Y1 - 2017/10/12 UR - http://ep.bmj.com/content/early/2017/10/12/archdischild-2017-313926.abstract N2 - Setting: Ten hospitals in Italy.Patients: Patients under the age of 18 with a diagnosis of oligoarticular juvenile idiopathic arthritis were eligible to receive intra-articular steroids in at least two joints or who had received a single joint injection in shoulder, elbow, wrist ankle or knee which had flared within 12 months of a joint injection were eligible for randomisation.Patients were excluded if they had received methotrexate, biologic disease-modifying drugs, intra-articular or systemic steroids within 3 months prior to enrolment. Non-Steroidal Antinflammatory Drugs NSAIDs were discontinued prior to enrolment. Patients with single knee arthritis were also excluded as this has the highest rate of 12-month remission.Intervention: 207 patients were randomised … ER -