TY - JOUR T1 - Fifteen-minute consultation: diagnosis and management of congenital CMV JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed SP - 232 LP - 235 DO - 10.1136/archdischild-2015-309656 VL - 101 IS - 5 AU - Tejshri Shah AU - Suzanne Luck AU - Mike Sharland AU - Seilesh Kadambari AU - Paul Heath AU - Hermione Lyall Y1 - 2016/10/01 UR - http://ep.bmj.com/content/101/5/232.abstract N2 - Congenital cytomegalovirus (cCMV) infection can result in permanent neurological problems and is a potentially preventable cause of sensorineural hearing loss in the UK. There is an urgency to diagnose and assess cCMV as antiviral treatment and has only been shown to be effective if started in the first 4 weeks of life. A recent randomised controlled trial of 6 months of treatment using oral valganciclovir has shown modest benefit in preventing hearing deterioration and in improving some neurodevelopmental outcomes. Parents and clinicians need to make a timely and informed choice regarding antiviral treatment and ensure that relevant non-pharmaceutical interventions are considered. This paper brings together the current evidence regarding the diagnosis and treatment of cCMV, consensus from two paediatric infectious diseases centres and outlines research priorities. ER -