PT  - JOURNAL ARTICLE
AU  - Tejshri Shah
AU  - Suzanne Luck
AU  - Mike Sharland
AU  - Seilesh Kadambari
AU  - Paul Heath
AU  - Hermione Lyall
TI  - Fifteen-minute consultation: diagnosis and management of congenital CMV
AID  - 10.1136/archdischild-2015-309656
DP  - 2016 Oct 01
TA  - Archives of disease in childhood - Education & practice edition
PG  - 232--235
VI  - 101
IP  - 5
4099  - http://ep.bmj.com/content/101/5/232.short
4100  - http://ep.bmj.com/content/101/5/232.full
SO  - Arch Dis Child Educ Pract Ed2016 Oct 01; 101
AB  - Congenital cytomegalovirus (cCMV) infection can result in permanent neurological problems and is a potentially preventable cause of sensorineural hearing loss in the UK. There is an urgency to diagnose and assess cCMV as antiviral treatment and has only been shown to be effective if started in the first 4 weeks of life. A recent randomised controlled trial of 6 months of treatment using oral valganciclovir has shown modest benefit in preventing hearing deterioration and in improving some neurodevelopmental outcomes. Parents and clinicians need to make a timely and informed choice regarding antiviral treatment and ensure that relevant non-pharmaceutical interventions are considered. This paper brings together the current evidence regarding the diagnosis and treatment of cCMV, consensus from two paediatric infectious diseases centres and outlines research priorities.