TY - JOUR T1 - What is next generation sequencing? JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed SP - 236 LP - 238 DO - 10.1136/archdischild-2013-304340 VL - 98 IS - 6 AU - Sam Behjati AU - Patrick S Tarpey Y1 - 2013/12/01 UR - http://ep.bmj.com/content/98/6/236.abstract N2 - Next generation sequencing (NGS), massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human genome can be sequenced within a single day. In contrast, the previous Sanger sequencing technology, used to decipher the human genome, required over a decade to deliver the final draft. Although in genome research NGS has mostly superseded conventional Sanger sequencing, it has not yet translated into routine clinical practice. The aim of this article is to review the potential applications of NGS in paediatrics. ER -