RT Journal Article SR Electronic T1 What is next generation sequencing? JF Archives of disease in childhood - Education & practice edition JO Arch Dis Child Educ Pract Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 236 OP 238 DO 10.1136/archdischild-2013-304340 VO 98 IS 6 A1 Sam Behjati A1 Patrick S Tarpey YR 2013 UL http://ep.bmj.com/content/98/6/236.abstract AB Next generation sequencing (NGS), massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human genome can be sequenced within a single day. In contrast, the previous Sanger sequencing technology, used to decipher the human genome, required over a decade to deliver the final draft. Although in genome research NGS has mostly superseded conventional Sanger sequencing, it has not yet translated into routine clinical practice. The aim of this article is to review the potential applications of NGS in paediatrics.