TY - JOUR T1 - Practical pharmacokinetics: what do you really need to know? JF - Archives of disease in childhood - Education & practice edition JO - Arch Dis Child Educ Pract Ed SP - 37 LP - 43 DO - 10.1136/archdischild-2013-304555 VL - 100 IS - 1 AU - E S Starkey AU - H M Sammons Y1 - 2015/02/01 UR - http://ep.bmj.com/content/100/1/37.abstract N2 - Having some understanding of pharmacokinetics is important for all clinicians when prescribing medications. Key elements to effective and safe prescribing include making sure that we don't underdose a medication making it ineffective, but also do not overprescribe a treatment known to cause toxic effects. In paediatrics, there are significant physiological and developmental differences that add to the challenges of safe prescribing. This article aims to provide the clinician with some basic paediatric pharmacokinetic principles with clinical examples to aid their prescribing skills. ER -