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Review ofPerkin MR, Bahnson HT, Logan K, et al. Association of early introduction of solids with infant sleep. A secondary analysis of a randomized clinical trial. JAMA Pediatr 2018;172:e180739.
Study design: This is a prospective, double-blinded, randomised, placebo controlled, non-inferiority trial.
Allocation: Randomisation was used with 1:1 ratio according to age group and trial phase, in blocks of 2, 4 or 6.
Study question
Setting: The setting was two hospitals in a malaria-endemic area of Malawi.
Patients: Patients studied were 3000 HIV-uninfected children, aged 2–59 months, who presented to the outpatient departments of the two sites and met the WHO criteria for the case definition of chest-indrawing pneumonia. Exclusion criteria included severe anaemia, severe respiratory distress at presentation, antibiotics …
Footnotes
Twitter @anna_ntovolou
Contributors AAN wrote the abstract; SM wrote the commentary; and both approved the final version.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.
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