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Structured abstracts of sentinel articles: Picket
Drug-free inactive disease in juvenile idiopathic arthritis can be achieved for 40% of patients
  1. Laura Chapman1,
  2. Amanda J Friend1,2
  1. 1 School of Medicine, University of Leeds, Leeds, UK
  2. 2 Department of Paediatrics, Leeds General Infirmary, Leeds, UK
  1. Correspondence to Dr Amanda J Friend, Paediatrics, Leeds General Infirmary, Leeds LS1 3EX, UK; amanda.friend{at}nhs.net

https://doi.org/10.1136/archdischild-2019-317833

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    Study design: randomised, single-blind trial.

    Study question

    Setting: The Netherlands.1

    Patients: 94 patients with new-onset (symptom duration <18 months) juvenile idiopathic arthritis (JIA) who had not been exposed to previous disease-modifying antirheumatic drug (DMARD) therapy.

    Interventions: conventional systemic DMARD monotherapy (methotrexate (MTX) or sulfasalazine) versus MTX plus 6-week tapered course of prednisolone vs MTX plus etarnercept.

    Outcomes: time to inactive disease; time to flare after the first episode of drug-free inactive disease (DFID).

    Main results: …

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    Footnotes

    • Contributors LC: wrote the abstract. AJF and LC: jointly wrote the commentary.

    • Provenance and peer review Not commissioned; internally peer reviewed.