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Midline mystery
  1. Helen Williams
  1. Correspondence to Helen Williams, Radiology Department, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, West Midlands B4 6NH, UK; helen.williams{at}

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Answers to the following two quiz questions can be found on page 239

Theme: midline brain abnormalities

For each of the following questions select one option from the following:

  1. Craniopharyngioma

  2. Septo-optic dysplasia

  3. Pituitary adenoma

  4. Posterior pituitary ectopia

  5. Germinoma

  6. Pituitary hypoplasia

  7. Hypothalamic hamartoma

Question 1

A 11-year-old girl presented with short stature and subsequent investigations revealed isolated growth hormone deficiency. A MRI scan was performed to look for any associated pituitary abnormalities. Figure 1 is a midline unenhanced, T1-weighted sagittal image of her brain. What does it show?

Figure 1

Question 2

A 6-year-old boy underwent MRI scan as part of his investigation for rapidly progressing central precocious puberty. What is the diagnosis based on this midline unenhanced, T1-weighted sagittal image (figure …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.